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EMF Study
(Database last updated on Mar 27, 2024)
ID Number |
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1442 |
Study Type |
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In Vitro |
Model |
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High voltage electrical stimulation of cells and analysis of molecule uptake (electroporation) |
Details |
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Yeast and erythrocytes were exposed to high voltage electric currents and analyzed for uptake of the 70 kDa molecule FITC-dextran and the 660 Da molecule propidium iodide by flow cytometry (via green or red fluorescence, respectively). The authors report that 20% of erythrocytes and 75% of yeast can take up the first test molecule within 5 minutes of a pulse. The uptake of the smaller propidium iodide molecule following initial uptake of FITC-dextran provides a measure of membrane recovery |
Findings |
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Effects (only at thermal levels) |
Status |
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Completed With Publication |
Principal Investigator |
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Harvard-MIT Health Sciences and Technology, USA
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Funding Agency |
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NIH, USA
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Country |
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UNITED STATES |
References |
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Smith, KC et al. Biophys J, (2008) 95:1547-1563
Weaver, JC J Radio Sci, (1995) 30:205-221
Bliss, JG et al. Bioelectrochem Bioenerg, (1989) 20:57-71
Weaver, JC et al. FEBS Letters, (1988) 229:30-34
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