ID Number		1919
Study Type		Epidemiology
Model		Loud Noise and Acoustic Neuroma (catch all)
Details		Loud Noise and Acoustic Neuroma (catch all). Many of the Interphone site studies have reported data on loud noise and acoustic neuroma as well. In the Swedish Interphone arm (n = 146 acoustic neuromas), the authors report an overall OR = 1.55; 95% CI 1.04-2.30, with increased ORs of 1.79; 95% CI = 1.11-2.89 for occupational exposure to machines and power tools and 2.25; 95% CI = 1.20-4.23 for loud music. Long term noise eposure (>13 yrs) also had an elevated OR = 2.12; 95% CI = 1.40-3.20). A follow-on study (2007) went beyond the Interphone data and enlisted 599 total acoustic neuroma cases through the Swedish Cancer Registry. In this study, a more detailed job exposure matrix was used to estimate occupational noise exposure, and the authors did NOT find any association with loud noise exposure even after allowing for a long latency period. The German Interphone study reported statistically significant correlations with loud noise (OR = 2.31; 95% CI = 1.15-4.66) as well as hay fever (OR = 2.20; 95% CI = 1.09-4.45). The French Interphone study (N = 108 acoustic neuroma cases) also reported correlations with loud noise overall (OR = 2.55; 95% CI = 1.35-4.82) as well as with loud music (OR = 3.88; 95% CI = 1.48-10.17) and occupational noise exposure (OR = 2.26; 95% CI = 1.08-4.72). The risk also increased with longer (>6yrs) noise exposure duration (OR = 3.15; 95% CI = 1.07-9.24).
Findings
Status		Completed With Publication
Principal Investigator
Funding Agency		?????
Country		UNITED STATES
References		Edwards, CG et al. Am J Epidemiol. , (2006) 163:327-333 Hours, M et al. Occup Environ Med., (2009) 66:480-486 Edwards, CG et al. Am J Epidemiol, (2007) 166:1252-1258 Edwards, CG et al. Am J Epidemiol, (2006) 163:327-333
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