ID Number		1960
Study Type		In Vitro
Model		900 MHz (GSM) exposure to neuronal cell lines and analysis of neuropathology
Details		SN56 (murine cholinergic) and rat primary cortical neurons were exposed to 900 MHz (GSM) at an SAR of 1 W/kg and assayed at different times during exposure over the course of 6 days for differentiation state. The authors report a decrease in neurite emission, outgrowth, and branching as well as the cortical neuron cytoskeleton regulating factor beta-thymosin. There was no effect on expression of early genes c-Fos and c-Jun. In a related study, co-exposure of RF as above exacerbated the effect of hydrogen peroxide on SN56 cells, but not rat primary neurons, and had no additional synergizing effect in either cell type in combination with glutamate or beta-amyloid protein
Findings		Effects
Status		Completed With Publication
Principal Investigator		Univ. Bologna, Italy
Funding Agency		Private/Instit.
Country		ITALY
References		Del Vecchio, G et al. Bioelectromagnetics, (2009) 30:564-572 Del Vecchio, G et al. Neurosci Lett, (2009) 455:173-177
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