ID Number		2122
Study Type		In Vivo
Model		50 Hz exposure to rats and analysis of sexual maturation and circulating hormone levels
Details		Pregnant Wistar rats were exposed to 50 Hz (ELF) at 10 kV/min for 24 hours during pregnancy. In addition, selected pups were exposed after birth until puberty. The authors report prenatal exposure resulted in decreased birth weight and weight gain as compared to sham exposed controls. After reaching puberty, however, weights between exposed and control rats remained similar. The authors also report sexual maturation was delayed and insuling-like growth hormone level reduced in the prenatally exposed group as compared to postnatal or sham exposure. There was also no difference in FSH, LH or E2 levels with exposure. Prenatal and postnatal exposure both lead to damage of the hypothalamus, pituitary gland, and ovaries.
Findings		Effects
Status		Completed With Publication
Principal Investigator		Suleyman Demirel University, Isparta, Turkey - bumindundar@gmail.com
Funding Agency		Private/Instit.
Country		TURKEY
References		Dundar, B et al. Toxicol Ind Health., (2009) 25:479-487
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