ICES Database
ElectroMagnetic Field Literature
Search Engine
  

EMF Study
(Database last updated on Mar 27, 2024)

ID Number 2526
Study Type In Vitro
Model Investigation of effects of in vitro RF-EMF exposure emitted from cellular phones on human sperm motility index, sperm DNA fragmentation and seminal clusterin (CLU) gene expression.
Details

AUTHORS' ABSTRACT: Zatala et al. 2015 (IEEE #6190): BACKGROUND: Use of cellular phones emitting radiofrequency electromagnetic field (RF-EMF) has been increased exponentially and become a part of everyday life. This study aimed to investigate the effects of in vitro RF-EMF exposure emitted from cellular phones on sperm motility index, sperm DNA fragmentation and seminal clusterin (CLU) gene expression. MATERIALS AND METHODS: In this prospective study, a total of 124 semen samples were grouped into the following main categories: i. normozoospermia (N, n=26), ii. asthenozoospermia (A, n=32), iii. asthenoteratozoospermia (AT, n=31) and iv. oligoasthenoteratozoospermia (OAT, n=35). The same semen samples were then divided into two portions non-exposed and exposed samples to cell phone radiation for 1 hour. Before and immediately after exposure, both aliquots were subjected to different assessments for sperm motility, acrosin activity, sperm DNA fragmentation and CLU gene expression. Statistical differences were analyzed using paired t student test for comparisons between two sub-groups where p<0.05 was set as significant. RESULTS: There was a significant decrease in sperm motility, sperm linear velocity, sperm linearity index, and sperm acrosin activity, whereas there was a significant increase in sperm DNA fragmentation percent, CLU gene expression and CLU protein levels in the exposed semen samples to RF-EMF compared with non-exposed samples in OAT>AT>A>N groups, respectively (p<0.05). CONCLUSION: Cell phone emissions have a negative impact on exposed sperm motility index, sperm acrosin activity, sperm DNA fragmentation and seminal CLU gene expression, especially in OAT cases.

Findings Effects
Status Completed With Publication
Principal Investigator Mansoura University, Mansoura, Egypt.
Funding Agency ?????
Country
References
  • Zalata, A et al. Int J Fertil Steril., (2015) 9:129-136
  • Comments

    Return