ID Number		407
Study Type		In Vivo
Model		915, 2450, 9400 MHz (CW) exposure to mice and analysis of cytogenetic effects in male germ cells
Details		CBA mice (male) were exposed to 915 MHz (CW), 2450 MHz (CW), and 9.4 GHz (CW) MW and analyzed for chromosome effects in testes. Following exposure to 2450 MHz (CW) MW for 6 hour/day over a 2 week period at 0.05 - 20 W/kg (whole body average), an SAR dependent increase in chromosome exchanges (aneuploidy, translocations, and the presence of univalents) was observed in germ cells exposed during spermatogenesis. Similar results were observed following exposure to BalbC mice to 9.4 GHz (PW- 0.5 usec pulse width 1 kHz repetition rate) for 1 hour/day at 1 - 100 mW/cm2 over 2 weeks. The authors interpreted these results as indicating athermal effects possibly due to resonant absorption by DNA.
Findings		Effects
Status		Completed With Publication
Principal Investigator		US Food & Drug Administration, USA - emc@cdrh.fda.gov
Funding Agency		FDA, USA
Country		UNITED STATES
References		Manikowska-Czerska, E et al. J Hered, (1985) 76:71-73 Manikowska, E et al. Experientia, (1979) 35:388-390
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